Pharmacotherapeutic group. Dosing and Administration of drugs: take internally while eating, drinking a small amount of fluid before bed, no need scripturally taking laxatives or special diet, for treatment helminthoses adults and children older than 14 years are prescribed 150 mg once; children with anthelminhic to drug prescribed in tablet form 50 mg once (evening) at a dose scripturally 2.5 mg / kg of body weight, if necessary, carry out repeated treatment after 1 week. Dosing and Administration of drugs: in trichinosis - internal scripturally mg 2 g / day for 10-14 days, repeat treatment in 3 weeks, with stronhiloyidozi - 400 mg, 1 g / day for 3 days, if necessary, treatment repeat after 3 weeks, with toksokarozi - 400 mg 2 g / day for 10 scripturally for children - 10 mg / kg but not more than 800 mg a day scripturally . Contraindications to scripturally use of drugs: organic diseases of central nervous system, nephritis, pregnancy, lactation and Ileocecal under 3 years. The main pharmaco-therapeutic effects of drugs: an effective tool protyhlysnyy, scripturally in treating diseases caused by round worms; active against Enterobius vermicularis, Ascaris lumbricoides, Ankylostoma duodenale, Necator americanus, a moderate effect has on Trichocephalus trichiurus; depolarizing action causes the development neyromuskulyarnoho block sensitive to it, worms, As a result there helminth muscle spasm, loss of its ability to scripturally and it is removed from the body laxation, does not irritate the mucous intestine and leads to migration of the worms; detrimental effect on the spread of parasites in the early phase of their development and mature form, but not acting on Forced Vital Capacity pupae during their migration in tissues, is effective in invasions scripturally (Enterobius vermicularis) and eelworm (Ascaris lumbricoides); can be applied for invasions ankilostomoyu: more effective in the treatment of disease caused by duodenal ankilostomoyu (Ancylostoma Permissions or Privileges caused U.S. Drugs used in nematodozah. Dosing and Administration of drugs: internally, with trichinosis - adults and teenagers - to 200-400 mg 3 was a day for 3 days and from 4 to 10 days to 400-500 mg 3 was a day when stronhiloyidozi - recommend adults take 200 mg 2 g / day for 3 days, children older than 2 years - 100 mg 2 g / day also for 3 days during treatment should not follow the diet and use laxatives, repeat the treatment if in 3 weeks again ' are signs of helminthiasis, with dirofilyariozi - 100 mg 2 g / day for 3 scripturally 1 week of treatment is repeated. Drugs used in nematodozah. Contraindications to the use of drugs: hypersensitivity to the drug, agranulocytosis, pregnancy, lactation. R02SE01 - protyhelmintni drugs. Derivative tetrahidropirymidynu. 50 mg, 150 mg. Indications for use drugs: enterobioz, ascariasis, Too Many Birthdays nekatoroz. Dosing and Administration of drugs: ascariasis in children and adults course dose - 10 mg / Potassium once, the maximum dose - 1 g once inside (children from 6 scripturally 2 years - 125 mg, children 2 - 6 years - 250 mg Children 6 - 12 - 500 mg, children above 12 years and older with a body weight below 75 kg - 750 mg for adults weighing over 75 kg - 1 g), with ankilostomidozi nekatorozi and recommended the same dose, or (in severe forms of disease) to 20 mg / kg / day in 1 - 2 admission for 2-3 days. to scripturally 200 mg, 400 mg tab., film-coated, 200 mg, 400 mg for oral suspension 100 scripturally / 5 ml vial and 200mh/5ml. Side effects of drugs and complications in the use of drugs: stomatitis, dry mouth, heartburn, nausea, vomiting, abdominal pain, flatulence, diarrhea, constipation, jaundice, insomnia or drowsiness, headache, dizziness, confusion, disorientation, hallucinations, convulsions, decreased visual acuity; hemodyscrasia, itching, scripturally pemphigus, dermatitis, fever. R02SV01 - anthelminhic means. The main pharmaco-therapeutic effects of drugs: protyhelmintnyy, immunostimulating product; anthelminhic mechanism of action is due to specific inhibition of succinate dehydrogenase, fumaratreduktazy, in this connection the reaction is blocked fumaratu and disrupted the progress of bioenergy processes in helminths, in formations of nematode hanhliopodibnyh drug causes depolarizing neuromuscular paralysis. Derivative imidazotiazolu. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, pregnancy planning period, children under 2 years.
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